South African President, Cyril Ramaphosa, is currently in Ghana for a 3-day state visit.
The visit is expected to culminate in an inaugural session of the bi-national commission.
It is also meant to deepen bilateral relations between Ghana and South Africa which has grown over the years, according to a statement.
Underlining these strong relations is the elevation of structured bilateral relations from permanent joint commission for cooperation to bi-national commission to be chaired by the head of state.
The South African leader is embarking on a week long four nation visit to the West African sub-region.
He has already visited Nigeria, Ivory Coast and is expected to visit Senegal after Ghana.